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1.
Advanced Functional Materials ; : 9, 2022.
Article in English | Web of Science | ID: covidwho-1925858

ABSTRACT

Bipolar junction transistors (BJTs), the basic building blocks of integrated circuits, are deployed to control switching applications and logic operations. However, as the thickness of a conventional BJT device approaches a few atoms, its performance decreases substantially. The stacking of atomically thin 2D semiconductor materials is advantageous for manufacturing atomically thin BJT devices owing to the high carrier density of electrons and holes. Here, an atomically thin n-p-n BJT device composed of heavily doped molybdenum ditelluride (n-MoTe2) and germanium selenide (p-GeSe) sheets stacked over each other by van der Waals interactions is reported. In a common-emitter configuration, MoTe2/GeSe/MoTe2 BJT devices exhibit a considerably high current gain (beta = I-c /I-b = 29.3) at V-be = 2.5 V. The MoTe2/GeSe/MoTe2 BJT device is employed to detect streptavidin biomolecules as analytes within m. Such vdW BJT devices can trigger the development of state-of-the-art electronic devices that can be used as biosensors to detect the various kinds of target DNA and proteins like spike protein of Covid-19.

2.
Bioscience Research ; 18(2):1198-1210, 2021.
Article in English | Web of Science | ID: covidwho-1405677

ABSTRACT

A novel virus is discovered recently, named as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). It causes the Coronavirus Disease 2019 (COVID-19), which is spreading rapidly worldwide. The emerging genetics and clinical evidence of the SARS-CoV-2 virus suggest a similar path to those of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). Coronavirus causes respiratory illness in humans and infect several other species of animals. It was one of the best interests of researchers as it attracted virologist's attention in last two decades. It was clear from an epidemic in 2002-2003 of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) that human civilization may have animal coronavirus as its potential threat in the future. However, the mechanism of this virus spreading from one specie to another remained obscure these years. The 2012 Middle East Respiratory Syndrome Coronavirus (MERS-CoV) epidemic of animals, and now this COVID-19 pandemic prioritizes the human coronavirus for further research and exploration. However, General hygiene, social distancing, and disinfection can prevent the person-to-person spread of coronavirus. This review focuses on SARS-CoV-2, which is emerged from China in December 2019 and caused a novel disease named as COVID-19. The current review has an insight to possible treatment COVID-19 followed by a short review of In silico candidate drug design and prevention;This systematic review was conducted according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines. Databases, including Health Research and Development Information network Plus (HERDIN Plus), Science direct, PubMed and google scholar were visited to search the articles. Further, the forecasting results of the fitted model show a significant decrease in the weekly global deaths from the 51th week of 2020 16th week of 2021 but 95% limit has also shown the potential of getting the situation worser amid COVID-19 second wave.

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